Researchers have successfully developed human brain organoids that can record the passage of time over multiple years, following human-specific endogenous programs, even outside the context of the organism.[2325][2344] These brain cells can mature and record time, which could help researchers understand how diseases affect the brain later in life by modeling how the brain changes over time.[2325][2344] The long-term potential of these brain organoids is significant, as they could provide valuable insights into neurological disorders and potentially lead to new treatments.[2325][2344] Studies have shown that brain organoids can be grown for years in a lab, which could revolutionize the way we understand brain development and function.[2344] The development of brain organoids that can record the passage of time over multiple years is a major breakthrough in the field of neuroscience and could have far-reaching implications for disease research.[2325][2344]